The global healthcare market is expected to reach USD 11,908.9 billion by 2022, growing at a CAGR of 8.9%. Germany stands as the 3rd largest market for healthcare and medical products and is No. 1 in Europe, and the country’s healthcare industry is growing at the rate of 5% per annum. The German medical device market is one of the most lucrative healthcare markets worldwide, with annual revenues of USD 35.8 billion, or 25.6 per cent of the European market. Artificial intelligence, big data, medical data analytics, medical data management are some of the technologies transforming the industry.

In this article, we have carefully curated a list of the top 10 healthcare startups based in Germany. The startups in this list are ranked according to the total funding they have raised to date. All these startups have distinguished themselves by the product or service they provide in the industry. Most of these startups are tech-enabled, meaning either their platform or product/service is digitally accessible. 

It is estimated that by 2030 there will be a global shortage of over 30 million health workers, which is four times more than the shortfall of 7 million estimated in 2013. Digitally enabled healthcare platforms help to reduce the burden of healthcare workers, allowing them to focus on more critical treatments and research. Tech-based medical care also helps in providing personalised treatment to clients in the comfort of their homes, thereby maintaining the social distancing requirement that emerged during COVID-19. CrunchBase and Pitchbook are the primary sources of data used in this article.

  1. Smart Reporting
  • Founders: Wieland Sommer MD, Marco Armbruster
  • Founding year: 2014
  • Headquarters: Munich, Bayern, Germany
  • Total Funding Received: €22,700,000
  • Investors: Eurostars, Yabeo Capital, Investitions- und Strukturbsnk Rheinland-Pfalz, Ann-Kristin Achleitner, Rolf Christof Dienst, Wessel Management, Wolfgang Reitzle
  • Latest Funding Round Type and Deal Amount: NA, Euro 15 million

Smart Reporting offers an intelligent software for physicians which improves quality and efficiency. The first platform was launched in radiology (www.smart-radiology.com) and supports radiologists in generating high-quality medical reports by applying guideline-compliant criteria in their reports. A template depicting the relevant criteria is filled in by the user; the corresponding report text is generated simultaneously. Additional information on the medical background is provided and all reported data are stored in a highly granular database and can be fully analysed. The software can be seamlessly integrated into other systems and can be combined with speech recognition and speech commands. Further, Smart Reporting provides an ideal tool to integrate AI and image analysis algorithms into the clinical workflow.

9. SpinDiag

  • Founders: Daniel Mark, Dominique Kosse, Frank Schwemmer, Gregor Czilwik, Mark Keller, Oliver Strohmeier
  • Founding year: 2016
  • Headquarters: Freiburg, Baden-Wurttemberg, Germany
  • Total Funding Received: €24,900,000
  • Investors: Think.Health
  • Latest Funding Round Type and Deal Amount: Series B, Euro 16.3 million

Spindiag is a spin-off of Hahn-Schickard, one of the world’s leading research institutions for microsystems technology. Based on its patented microfluidic platform “LabDisk”, Spindiag develops an easy-to-use, compact, and automated point-of-care system for the broad, fast, and affordable screening for respiratory pathogens such as SARS-CoV-2 or drug-resistant pathogens. The company’s system consists of an analysis device with an integrated test cartridge that makes manual pipetting of swab samples onto the test carrier unnecessary and reduces the risk of infection for users to a minimum, enabling doctors to integrate the test system into everyday clinical practice, at the point of care in a hassle-free manner.

8. Medwing

  • Founders: Johannes Roggendorf, Timo Fischer
  • Founding year: 2017
  • Headquarters: Berlin, Berlin, Germany
  • Total Funding Received: USD 30,740,011
  • Investors: Northzone, Atlantic Labs, Cherry Ventures, Cathay Innovation, H14, Quadrille Capital, Sebastian Pollok, Adevinta Ventures
  • Latest Funding Round Type and Deal Amount: NA

Medwing offers a staffing platform developed to arrange short-term and permanent jobs in the healthcare industry. The startup’s platform simplifies hiring and provides healthcare professionals with employment opportunities ranging from temporary and permanent staffing to cross-border placements, enabling medical personnel and doctors to find their dream jobs by partnering directly with the leading healthcare institutions in Europe.

7. Breakpoint Therapeutics

  • Founders: Daniel Speidel, Jonathan Hollick
  • Founding year: 2019
  • Headquarters: Hamburg, Hamburg, Germany
  • Total Funding Received: Euro 30 million
  • Investors: Medicxi Ventures, Evotec, Taiho Ventures
  • Latest Funding Round Type and Deal Amount: NA, Euro 30 million

Breakpoint Therapeutics aims to advance the clinical development of first-in-class oncology drugs that interfere with DNA repair and replication stress tolerance pathways. The company’s therapeutics target the DNA damage response in cancer cells with repair and replication stress tolerance pathways, enabling the medical organisation and hospitals to develop drugs that succeed and complement PARP inhibitors and facilitate the cure of therapy-resistant cancers.

6. OMEICOS Therapeutics

  • Founders: Karen Uhlmann, Robert Fischer, Dominik Muller, John Falck
  • Founding year: 2013
  • Headquarters: Berlin, Berlin, Germany
  •  Total Funding Received: USD 37,310,346
  • Investors: High-Tech Grunderfonds, IBB Ventures, KfW, Forbion Capital Partners, Vesalius Biocapital Partners, BMBF, VC Fonds Technology Berlin, Remiges Ventures, SMSgroup, Ascenion GmbH, SICAR, The Falck Revocable Trust, KG Investments
  • Latest Funding Round Type and Deal Amount: Series C, Euro 17 million

OMEICOS Therapeutics is a biopharmaceutical company developing first-in-class small molecule therapeutics to prevent and treat cardiovascular diseases, including atrial fibrillation. The company’s novel therapeutic strategy is based upon the discovery of natural CYP-P450 generated metabolites of omega-3 fatty acids, so-called epoxy eicosanoids. This new class of bioactive lipid mediators activates type-specific cellular endogenous pathways that can be therapeutically deployed in inflammatory, cardiovascular, and other diseases. OMEICOS has discovered a series of metabolically robust synthetic analogues of omega-3 fatty acid-derived epoxy eicosanoids. These small molecules are orally available and show significantly improved biological activity and pharmacokinetic properties compared to their natural counterparts.

5. AMBOSS

  • Founders: Benedikt Hochkirchen, Jan Sievert Weiss, Kenan Hasan, Madjid Salimi, Nawid Salimi
  • Founding year: Dec 1, 2012
  • Headquarters: Berlin, Berlin, Germany
  • Total Funding Received: USD 39,076,352
  • Investors: Partech, Wellington Partners, Target Global, Cherry Ventures, Holtzbrinck Digital
  • Latest Funding Round Type and Deal Amount: Series B, Euro 30 million

AMBOSS is a medical technology startup with offices in New York, Berlin, Cologne and Cagliari. Its knowledge platform has fundamentally changed the way medical know-how is acquired and utilised at the point of care. Students use the interactive library and high-yield question bank for general study and exam preparation, while clinicians rely on AMBOSS to make effective clinical decisions guided by evidence-based recommendations.

4. Wellster Healthtech Group

  • Founders: Manuel Nothelfer, Nico Hribernik
  • Founding year: Nov 2018
  • Headquarters: Munich, Bayern, Germany
  • Total Funding Received: USD 41,691,831
  • Investors: HV Capital, SevenVentures, MPGI, German Media Pool, HGDF, Dermapharm, Constantin Bisanz, Jean-Remy von Matt
  • Latest Funding Round Type and Deal Amount: NA, Euro 35 million

Wellster Healthtech Group provides telemedical platform solutions intended to offer a new type of access to medical solutions. The company’s platform combines telemedicine, drug, and digital therapies and provides portals for mental health and medical self-tests, thereby helping customers by making mental health and medical home tests easier.

3. Avi Medical

  • Founders: Christoph Baumeister, Julian Kley MD, Vlad Lata
  • Founding year: 2020
  • Headquarters: Munich, Bayern, Germany
  • Total Funding Received: USD 46,866,953
  • Investors: Idinvest Partners, Picus Capital, Claret Capital Partners, Operator Partners, Addition, Vorwerk Ventures, 3VC, Daniel Dines, Heal Capital
  • Latest Funding Round Type and Deal Amount: Series A, Euro 28.5 million

Avi Medical is a digital healthcare startup that offers telemedicine services. The company’s services let patients book appointments at any time, manage their health data, chat with the practitioner and make video calls, enabling clients to receive the best possible care. It aims to empower doctors and patients to work together towards better health.

2. PlusDental

  • Founders: Lukas Brosseder, Peter Baumgart, Peter Baumgart, Constantin Bisanz, David Khalil
  • Founding year: 2017
  • Headquarters: Berlin, Berlin, Germany
  • Total Funding Received: USD 88,038,178
  • Investors: HV Capital, Lakestar, Kreos Capital, Saarbruecker 21, Ping An Global Voyager, Roman Kirsch, Sebastian Pollok, Elephant & Castle Capital, Cadence Growth Capital, Jebsen Capital, Mario Gotze, Bruce Darnell
  • Latest Funding Round Type and Deal Amount: Angel round, NA

PlusDental’s transparent dental aligners are developed to offer a modern alternative to teeth braces. The startup relies on state-of-the-art 3D techniques, cooperation with leading orthodontists and dentists to offer invisible tooth rails for correcting dental misalignments, enabling patients to have a brighter smile by aligning their teeth with invisible splints.

1. IOmx Therapeutics

  • Founders: Patrick Baeuerle, Elmar Maier, Nisit Khandelwal, Philipp Beckhove, Sebastian Meier-Ewert
  • Founding year: 2016
  • Headquarters: Munich, Bayern, Germany
  • Total Funding Received: €105,000,000
  • Investors: MPM Capital, Sofinnova Partners, Wellinton Partners, M Ventures, MIG, ATHOS Service
  • Latest Funding Round Type and Deal Amount: Series B, Euro 65 million

iOmx Therapeutics is a new-age biotech startup in the immuno-oncology field. It intends to address the novel immune checkpoint modulators on tumor cells. The company’s therapeutics focus on systematically screening human tumor cells, breaking down the inherent resistance mechanisms of tumors against immune attack often mediated by cell surface molecules that stimulate immune-inhibitory receptors on T cells, enabling healthcare institutions to offer cancer immune-checkpoint therapy.


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Manish writes about the startup ecosystem on VCBay. He is pursuing Master of Commerce from Delhi School of Economics, University of Delhi, and is passionate about the world of finance, information technology & entrepreneurship.

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